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Question:

Can I run 32-bit programs on 64-bit nodes

Answer:

Yes, 32-bit programs can migrate to 64-bit nodes (and even start there), but the home-node of 32-bit programs must be on a 32-bit node.. Thus, if you want to run 32-bit programs on predominantly 64-bit cluster(s), you may consider leaving aside a few 32-bit nodes as part of your cluster and/or multi-cluster, from where you can start 32-bit programs.